Principle of gas chromatograph for detecting ethylene oxide content in medical supplies
This method uses headspace gas chromatography, a chromatographic technique that adds a headspace sampling device in front of the gas chromatograph inlet. The GC589 gas chromatograph developed by Nanjing Kejie Analytical Instrument Application Research Institute The sampler is used in conjunction with a gas chromatograph. It uses the tested sample (gas-liquid and gas-solid) to heat and balance, and then takes the part of its volatile gas into the gas chromatograph. It is dedicated to the analysis of volatile trace components, such as methanol, ethanol and many other volatile organic solvents; floral aromas, perfumes of different seasons, Chinese herbal medicines with volatile components; special smell of vegetables and condiments, etc. It can be used for quantitative analysis. The detection solution for residual solvents in medical supplies is to use a headspace sampler for sample separation and capillary column separation, and the hydrogen flame detector to detect the residual solvent content. This method is simple to operate, has good effect, and high efficiency. Bacterial quality control necessary testing program.
Reference standard and applicable scope of ethylene oxide detection method
This method refers to GB / T16886.7-2001, which is suitable for sterilization of medical supplies. Residues in gauze and plastic medical supplies, especially medical devices, are increasingly used in ethylene oxide sterilization. widely. The quality of ethylene oxide has a significant impact on the sterilization effect, and the residual ethylene oxide in the sterilized items is also harmful to the health of patients and medical personnel. Medical equipment used for extracorporeal circulation, ethylene oxide is more toxic to humans and animals than carbon tetrachloride and chloroform, similar to ammonia. Ethylene oxide is corrosive to the eyes and respiratory tract, and can cause vomiting, nausea, diarrhea, headache, central depression, dyspnea, pulmonary edema, etc. Liver and kidney damage and hemolysis can also occur. Excessive skin contact with liquid or solution of ethylene oxide produces a burning sensation, blisters, dermatitis, etc. If absorbed through the skin, a systemic reaction may occur.
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